Education

Learn about aging clocks

Evidence-based articles that explain the science, separate hype from substance, and help you make informed decisions. No jargon walls.

Fundamentals8 min

What is biological age?

The difference between chronological and biological age, why it matters, and what science actually knows (and doesn't know) about measuring it.

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Clock Science12 min

How epigenetic clocks work

From Horvath's pan-tissue clock to DunedinPACE: how DNA methylation patterns are used to estimate biological age, and why different clocks give different answers.

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Clock Science10 min

ChronAge vs PhenoAge vs Pace-of-Aging

Understanding the three paradigms of aging clocks: those trained to predict your calendar age, those trained to predict health outcomes, and those measuring your current rate of aging.

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Critical Perspective10 min

The limitations of aging clocks

What a single biological age number hides: organ heterogeneity, cell-mixture confounding, measurement uncertainty, and the gap between vendor claims and evidence.

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Practical7 min

What your test results actually mean

You got your biological age result. Now what? How to interpret the number, what it doesn't tell you, and when to talk to a doctor.

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Interventions9 min

Exercise and biological age: what the evidence shows

How physical activity affects epigenetic clocks, inflammatory markers, and phenotypic aging scores. The most consistently validated intervention.

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Want to start with the basics?

Our Start Here guide walks you through everything step by step.

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