How epigenetic clocks work
From Horvath's pan-tissue clock to DunedinPACE: how DNA methylation patterns are used to estimate biological age, and why different clocks give different answers.
Coming soon →Education
Evidence-based articles that explain the science, separate hype from substance, and help you make informed decisions. No jargon walls.
The difference between chronological and biological age, why it matters, and what science actually knows (and doesn't know) about measuring it.
Read article →From Horvath's pan-tissue clock to DunedinPACE: how DNA methylation patterns are used to estimate biological age, and why different clocks give different answers.
Coming soon →Understanding the three paradigms of aging clocks: those trained to predict your calendar age, those trained to predict health outcomes, and those measuring your current rate of aging.
Coming soon →What a single biological age number hides: organ heterogeneity, cell-mixture confounding, measurement uncertainty, and the gap between vendor claims and evidence.
Coming soon →You got your biological age result. Now what? How to interpret the number, what it doesn't tell you, and when to talk to a doctor.
Coming soon →How physical activity affects epigenetic clocks, inflammatory markers, and phenotypic aging scores. The most consistently validated intervention.
Coming soon →Our Start Here guide walks you through everything step by step.
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